Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIDIQGIKEALPHRYPMLLVDRVLEVSED-TIVAIKNVTINEPFFNGHFPQYPVMPGVLIMEALAQTAGVLEL-SKPENKGKLVFYAGMDKVKFKKQVVPGDQLVMTATFVKRRGT--IAVVEAKAEVDGKLAAS-GILTFAIGN 3AZB Chain:A ((11-152)) -IDIEDIKKILPHRYPFLLVDKVIYMQPNKTIIGLKQVSTNEPFFNGHFPQKQIMPGVLQIEALAQLAGILCLKSDDSQKNNLFLFAGVDGVRWKKPVLPGDTLTMQANLISFKSSLGIAKLSGVGYVNGKVVINISEMTFAL--

General information: TITO was launched using: RESULT: Template: 3AZB.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 613 -64415 -105.08 -470.18 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.84 3D Compatibility (PKB) : -105.08 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.84 QMean score : 0.532

(partial model without unconserved sides chains): PDB file : Tito_3AZB.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3AZB-query.scw PDB file : Tito_Scwrl_3AZB.pdb: