Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MWVKDMFILGSGDQGLAVLSIYEGEVEGLV--DIFEEGRFIGCKILDKTVLGGLKWFESLLLTLDRKPRAIVAFGDNFKREEIFCS-YKNKVEYINVICNSARIFKHSFLGK--GNFIGTNVTIQALVEIGDNNIINSGSIVSCNCKIGNNVNISPGVILSGNVKIDDNVFIGAGATIRDAVSIGFGAIIGAGATVIHNVPENAVVVGTPGKIIKYRSV 5T2Y Chain:A ((5-196)) -------------ARTEKIYIYGASGHGLVCEDVAKNMGYKECIFLDD--F--MK-FESTLPKYD----FFIAIGNNEIRKKIYQKISENGFKIVNLIHKSALISPSAIVEENAGILIMPYVVINAKAKIEKGVILNTSSVIEHECVIGEFSHVSVGAKCAGNVKIGKNCFLGINSCVLPNLSLADDSILGGGATLVKNQDEKGVFVGVPAK-------

General information: TITO was launched using: RESULT: Template: 5T2Y.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1115 -23323 -20.92 -126.07 target 2D structure prediction score : 0.50 Monomeric hydrophicity matching model chain A : 0.74 3D Compatibility (PKB) : -20.92 2D Compatibility (Sec. Struct. Predict.) : 0.50 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.365

(partial model without unconserved sides chains): PDB file : Tito_5T2Y.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5T2Y-query.scw PDB file : Tito_Scwrl_5T2Y.pdb: