Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKSYQAVYQILSK-ETDYISGEKIAEKLSLSRTSIWKAIKRLEQEGIEINSIKNRGYKLMN-GDLILPEILEENLPIKVSFK-----PETKSTQLDAKEAIDLGHEANTLYLASYQTAGRGRFQRSFYSPQG-GIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNLTLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFT--IKDFPQELKEKAASL-FKATAPITR----NELIIEI---WRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYKGLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK 3V7R Chain:A ((9-329)) -KYSQDVLQLLYKNKPNYISGQSIAESLNISRTAVKKVIDQLKLEGCKIDSVNHKGHLLQQLPDIWYQGIIDQYTKSSALFDFSEVYDSIDSTQLAAKKSL-VGNQSSFFILSDEQTKGRGRFNRHWSSSKGQGLWMSVVLRPNVAFSMISKFNLFIALGIRDAIQHFSQDEVKVKWPNDIYIDNGKVCGFLTE-MVANNDG-IEAIICGIGINLTQQLENFDESIRHRATSIQLHDKNKLDRYQFLERLLQEIEKRYNQFLTLPFSEIREEYIAASNIWNRTLLFTENDKQFKGQAIDLDYDGYLIVRDEAGESHRLISADIDF----

General information: TITO was launched using: RESULT: Template: 3V7R.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1500 60427 40.28 199.43 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.79 3D Compatibility (PKB) : 40.28 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.533

(partial model without unconserved sides chains): PDB file : Tito_3V7R.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3V7R-query.scw PDB file : Tito_Scwrl_3V7R.pdb: