Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRRTRMSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSGIDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVLACLREPLPASHYMIAVAGKD-VRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAGAQNLLNAFNIVEEVEYCAKIYCLAKNFGEPV-VLPDEEMELMAEKFKTYGQRK 1DZZ Chain:P ((1-208)) MERNKLA---RQIIDTCLEMTRLGLNQGTAGNVSV--RYQDGMLITPTGIPYEKLTESHIVFIDGNGKHEEG-KLPSSEWRFHMAAYQSRPDANAVVHNHAVHCTAVSILNRSIPAIHFMIAAAGGNSIPCAPYATFGTRELSEHVALALKNRKATLLQHHGLIACEVNLEKALWLAHEVEVLAQLYLTTLAITDPVPVLSDEEIAVVLEKFKT-----

General information: TITO was launched using: RESULT: Template: 1DZZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain P - contact count / total energy / energy per contact / energy per residue : 1104 -78973 -71.53 -383.36 target 2D structure prediction score : 0.71 Monomeric hydrophicity matching model chain P : 0.84 3D Compatibility (PKB) : -71.53 2D Compatibility (Sec. Struct. Predict.) : 0.71 1D Compatibility (Hydrophobicity) : 0.84 QMean score : 0.478

(partial model without unconserved sides chains): PDB file : Tito_1DZZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1DZZ-query.scw PDB file : Tito_Scwrl_1DZZ.pdb: