Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTD---------INDYEDAEDSAVDEDEAKAAESGAADEEAGNLTDADLAEAETLTVTAKQKQRQALEDEVAAFLARGGRITEVPPDEHSDR-- 2KRX Chain:A ((1-94)) MPDPLMYQQDNFVVLETNQPEQFLTTIELLEKLKGELEKISFSDLPLELQKLDSLPAQAQHLIDTSCELDVGAGKYLQWYAVRLEKLEHHHHHH

General information: TITO was launched using: RESULT: Template: 2KRX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 290 33909 116.93 408.54 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : 116.93 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.271

(partial model without unconserved sides chains): PDB file : Tito_2KRX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2KRX-query.scw PDB file : Tito_Scwrl_2KRX.pdb: