Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIQFDQVSLRRGGRVLFQKASMQL-HPGWKIGLTGVNGAGKSTLFAALLGSLGADEGSLTRPSVWTVAHMAQEVKALDMPAIDFVLSGDEEYWD-IQNKLAQP---EQLTD-------SDLAKLHGRFDEIHGYSAPSKAAQLMAGLGFLEHQLRLNVASFSGGWRMRLNLARTLMSRSDLLLLDEPTNHLDLDAILWLEDWLK--AYEGTLILI-SHDRDFLDAITDHILHIENQELTLYTGNYSTFETTRSERLAQQQQAFEKQQEARAHLQKFIDRF-KAKATKARQAQSRIKQLERMQQLAPAHVDTPFTFSFREPTKMSSPLLTLENASIGYGDKKIAEKIKLQITPNS-----RIGLLGMNGAGKSTLIKSLVG-DLPLLAGERKASELLNIGYFAQHQMDALDGQASPMLQLARIADKQISEATLRS-FLGSFGFSGERMDTPCESFSGGERARLALALIVWQRPNVLILDEPTNHLDLDMRHALSMALQDF----EGAVVLVSHERQLIASVCDELLLVHGGKCTEFEGDLQDYAKWLREARQQQINAQTAVAQNNSSSAAPAPAKVDKEAQRKEAARRREQTRPIRKNIEKVESQIEKLQPRLAEIEEALADTSLYEANRKDDLLKLMNEQTELKAKLEQYEEQLLELMMELEEMEASFEN 5LW7 Chain:B ((78-533)) --QLDEDCVHRYGVNAFVLYRLPIVKDGMVVGIVGPNGTGKTTAVKILAGQL--------------IPNLCEDNDSWDNVIRAFRGNELQNYFERLKNGEIRPVVKPQYVDLLPKAVKGKVRELLKKVDEVGKFEEVVKELELENVLDRELHQL-------SGGELQRVAIAAALLRKAHFYFFDEPSSYLDIRQRLKVARVIRRLANEGKAVLVVEHDLAVLDYLSD-VIHVVYGEPGVYG-------------------IFSKPKGTRNGINEFLQGYLKDENVRFRPYEIRFTKLSE-------RVDVE-----RE-TLVEYPRLVKDYGSF-----------KLEVEPGEIRKGEVIGIVGPNGIGKTTFVKMLAGVEEPT---EGKVEWDLTVAYKPQYIKAEYEGTVYELL--SKIDSSKLNSNFYKTELLKPLGII-DLYDRNVEDLSGGELQRVAIAATLLRDADIYLLDEPSAYLDVEQRLAVSRAIRHLMEKNEKTALVVEHDVLMIDYVSDRLIVFEG---------------------------------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 5LW7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 2047 38702 18.91 90.21 target 2D structure prediction score : 0.49 Monomeric hydrophicity matching model chain B : 0.70 3D Compatibility (PKB) : 18.91 2D Compatibility (Sec. Struct. Predict.) : 0.49 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.358

(partial model without unconserved sides chains): PDB file : Tito_5LW7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5LW7-query.scw PDB file : Tito_Scwrl_5LW7.pdb: