Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDSNMEVLIKTEDAIDAYNGAANLARSLGVSRAAISQ-----WGEY----VPEVSARGLVILQPSIPHIIKKPSAT 5CM3 Chain:A ((38-91)) ---------------------ATFATSLGLTRGAVSQAVHRVWAAFEDKNLPEGYARVTAVLPEHQAYIVRKWEA-

General information: TITO was launched using: RESULT: Template: 5CM3.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 34 -7373 -216.85 -163.84 target 2D structure prediction score : 0.51 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -216.85 2D Compatibility (Sec. Struct. Predict.) : 0.51 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.427

(partial model without unconserved sides chains): PDB file : Tito_5CM3.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5CM3-query.scw PDB file : Tito_Scwrl_5CM3.pdb: