Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETDGYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVFQAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGS-RYHRRPGSMGP-VAPNRVFKNKRLAGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK 5DM6 Chain:B ((2-204)) --KGILGTKIGMTQIW-KNDRAIPVTVVLAGPCPIVQRKTAQTDGYEAVQIGYAPKAERKVNKPMQGHFAKAGVAPTRILREFR----GFAPDGDSVNVDIFAEGEKIDATGTSKGKGTQGVMKRWNFAGGPASHGSKKWHRRPGSIGQRKTPGRVYKGKRMAGHMGMERVTVQNLEVVEIRAGENLILVKGAIPGANGGLVVLRSAAKA-

General information: TITO was launched using: RESULT: Template: 5DM6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 828 -4619 -5.58 -22.98 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain B : 0.85 3D Compatibility (PKB) : -5.58 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.85 QMean score : 0.385

(partial model without unconserved sides chains): PDB file : Tito_5DM6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5DM6-query.scw PDB file : Tito_Scwrl_5DM6.pdb: