Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACETSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSPDIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRLADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEKVVKEVIPAELLDD-QTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFSGKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVPEEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALKASLAK 5H9U Chain:C ((19-408)) MRALRLVTSESVTEGHPDKLADRISDAILDALIAQDKKARVAAETLVTTGLVFVAGEITTEGYVDIPNLVRKTVREVGYTRAKYGFDADTCAVLTAIDEQSPDIAGGVNLSYEWRVLKSTDPLDRVGAGDQGLMFGYATDETPELMPLPITLAHRLTMRLAEVRKTGLLPYLRPDGKAQVTVVYEGD-KPLYVKTVVVSAQHSPEVEQEQLREDLIREVVRQAIPPEYLKDGETEYLINPSGRFILGGPHADTGLTGRKIIVDTYGGAVPHGGGAFSGKDPTKVDRSASYYARYMAKNIVAAGLARRALVELAYAIGKARPVSLRVETFGTGVLPDEKLTEIAKKVFDPRPLAIIEELDLLRPIYTPTSAYGHFGRP--GFPWEETDRVEALR-----

General information: TITO was launched using: RESULT: Template: 5H9U.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 2389 -70594 -29.55 -181.47 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain C : 0.90 3D Compatibility (PKB) : -29.55 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.90 QMean score : 0.546

(partial model without unconserved sides chains): PDB file : Tito_5H9U.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5H9U-query.scw PDB file : Tito_Scwrl_5H9U.pdb: