Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREMPFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRG-LEVYPEGFLEYLQNFEFKATVRSAREGELVFANEPL----------IQVEGPLAHCQLVETALLNMV------------NFQTLIATKAARIKSVIGED-PLLEFGTRRAQEL---DAAVWGTRAAYIGGAD-------ATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAFMAYAKTHKDC-----------VFLVDTY---DTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVREQ----LDAAGFTEAKIYA-SNDLDEA-TILNLKMQKAKIDVWGVGTKLITAYDQPA--------LGAVFKLVSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEEAIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEEYKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA 1VLP Chain:A ((22-409)) -----------LDTDMYKITMHAAVF-TNFPDVTVTYKYTNRSSQLTFNKEAINWLKEQFSYLGNLRFTEEEIEYLKQEIPYLPSAYIKYISSSNYKL----HPEEQISFTSEEIEGKPTHYKLKILVSGSWKDTILYEIPLLSLISEAYFKFVDIDWDYENQLEQAEKKAETLFDNGIRFSEFGTRRRRSLKAQDLIMQGIMKAVNGNPDRNKSLLLGTSNILFAKKYGVKPIGTVAHEWVMGVASISEDYLHANKNAMDCWINTFGAKNAGLALTDTFGTDDFLKSFRPPYSDA---------YVGVRQDSGDPVEYTKKISHHYHDVLKLPKFSKIICYSDSLNVEKAITYSHAAKENGMLATFGIGTNFTNDFRKKSEPQVKSEPLNIVIKLLEVNGNHA-----IKISDNLGK--------------------------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 1VLP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1488 4653 3.13 14.27 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : 3.13 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.372

(partial model without unconserved sides chains): PDB file : Tito_1VLP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1VLP-query.scw PDB file : Tito_Scwrl_1VLP.pdb: