Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEH-GLKYDFVQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFILSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPIDPSRAIMSEKDHRHPTLKEFEAENPFVYGEI 2IXJ Chain:A ((4-173)) MKATRLAIPDVILFEPRVFGDDRGFFFESYNQRAFEEACGHPVSFVQDNHSRSAR-GVLRGLHYQIRQA-QGKLVRATLGEVFDVAVDLRRGSPTFGQWVGERLSAENKRQMWIPAGFAHGFVVLSEYAEFLYKTTDFWAPEHERCIVWNDPELKIDWPLQDA-PLLSEKDRQ------------------

General information: TITO was launched using: RESULT: Template: 2IXJ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 867 -28312 -32.65 -167.52 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.83 3D Compatibility (PKB) : -32.65 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.452

(partial model without unconserved sides chains): PDB file : Tito_2IXJ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2IXJ-query.scw PDB file : Tito_Scwrl_2IXJ.pdb: