Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSGSTITPWVVGNWKMNPMRANANQLIEEFKQLLQQNQIADENCHVGVAPVSIALTTVQAQLQDAARTVYTVAQDVSRVAGTGAYTGEVSAELLKDSQINFVLVGHSERRDIFGDNVEILKAKLQNALNAGMTVIYCVGESLEQREQGQAEQVVLQQICDIAPVVTAEQWQNQVVIAYEPIWAIGTGKTASPQDAQAMHAKIR---EGLCQLTPAGSNIAILYGGSVKAENAVELAACPDINGALVGGASLNAASFYQIVQAFAQSK 1O5X Chain:A ((6-246)) --------FVAANWKCNGTLESIKSLTNSFNNL----DFDPSKLDVVVFPVSVHYDHTRKLLQSKFSTG---IQNVSKF-GNGSYTGEVSAEIAKDLNIEYVIIGHFERRKYFHETDEDVREKLQASLKNNLKAVVCFGESLEQREQNKTIEVITKQVKAFVDLI--DNFDN-VILVYEPLWAIGTGKTATPEQAQLVHKEIRKIVKDTCGEKQA-NQIRILYGGSVNTENCSSLIQQEDIDGFLVGNASL-KESFVDIIKS-----

General information: TITO was launched using: RESULT: Template: 1O5X.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1230 -90199 -73.33 -378.99 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.80 3D Compatibility (PKB) : -73.33 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.80 QMean score : 0.543

(partial model without unconserved sides chains): PDB file : Tito_1O5X.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1O5X-query.scw PDB file : Tito_Scwrl_1O5X.pdb: