Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTIEPGQRIALVGQSGSGKSTLSKIPSGLYKIDTGKVLFDGVNINQIDKKILSQNLGVVPQDSFLLNRSILDNIT--LKHEVTSQKIEEVCKAVQIYDEIMAMPMKFNTIISEMGSNISGGQRQRIALARALINNPSIVILDEATSALDTINEERITKYI----KSQGCTQIIVAHRLSTIKDADIIVVMKGGKIVESGNHKYLMDLGGEYYSLYTKRK 2IXF Chain:B ((40-253)) FTLYPGKVTALVGPNGSGKSTVAALLQNLYQPTGGKVLLDGEPLVQYDHHYLHTQVAAVGQEPLLFGRSFRENIAYGLTRTPTMEEITAVAMESGAHDFISGFPQGYDTEVGETGNQLSGGQRQAVALARALIRKPRLLILDQATSALDAGNQLRVQRLLYESPEWASRTVLLITHQLSLAERAHHILFLKEGSVCEQGTHLQLMERGGCYRSM-----

General information: TITO was launched using: RESULT: Template: 2IXF.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 946 -28371 -29.99 -136.40 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain B : 0.80 3D Compatibility (PKB) : -29.99 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.80 QMean score : 0.483

(partial model without unconserved sides chains): PDB file : Tito_2IXF.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2IXF-query.scw PDB file : Tito_Scwrl_2IXF.pdb: