Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTKKIVAIWAQDEEGLIGKENRLPWHLPAELQHFKETTLNHAILMGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQDQEKNLYIIGGKQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTIQYRKRKEV 3TQ9 Chain:A ((3-160)) ----ITLIAAMDKNRLIGRNNELPWHLPADLAHFKSITLGKPIVMGRRTFDSIGKP-LPHRRNIVITQQKNLIIEGCDIFYSLDDALSALT-KEPEVIIIGGARIFKEALPKADKMILTIINHSFEGDVYFPEWNDKE-WKITSQIKH---------FQFLELRR---

General information: TITO was launched using: RESULT: Template: 3TQ9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 703 -117932 -167.76 -791.49 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : -167.76 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.589

(partial model without unconserved sides chains): PDB file : Tito_3TQ9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3TQ9-query.scw PDB file : Tito_Scwrl_3TQ9.pdb: