Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSSLSQVNADVLKQAQQRIQQDLLTTLAAFSIPEPLKSAVHHAVMLGGKRVRPALCYATASLQDNPNFAAARRAAVAVELIHCYSLAHDDLPCMDNDLLRRGQPTCHVAFGEDTALLAGDILQSMAFEVLGSRLFDEQGQGTDAAIVLKQIQILATA--SSKMVCGQVLDLQAEAK--QISQDELENIHRNKTGALIQAAIMMGAVTIFPGTDQAIPKLRQYGQAIGLAFQVQDDILDITSSTETLGKTAGKDEQVQKSTYPALMGLEQAQIYAKELHDQAFEALAHFGENAKELVEISQFLLARTN 3LVS Chain:B ((6-287)) ---------ERLKEIQDAVETAMAAAIGRL-PAGDLRDAMAYAA-QGGKRLRAFLAIESAAIH-GISMAQAMPAALAVEALHAYSLVHDDMPCMDNDDLRRGLPTVHKKWDDATAVLAGDALQTLAFELCTDPVLG------SAENRVALVAALAQASGAEGMVYGQALDIAAETAAVPLTLDEIIRLQAGKTGALISFAAQAGAIL-AGADR---GPLTAYATALGLAFQIADDILDVE------------DAEAHKATFVSLLGLAGAKSRAADLVAEAEAALAPYGEAASTLRACARYVIE---

General information: TITO was launched using: RESULT: Template: 3LVS.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1310 -135330 -103.30 -508.76 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain B : 0.76 3D Compatibility (PKB) : -103.30 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.546

(partial model without unconserved sides chains): PDB file : Tito_3LVS.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3LVS-query.scw PDB file : Tito_Scwrl_3LVS.pdb: