Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MCRILGLSRQSYYYQSKPKKD-----------------ESELEEVVAEEFIRSRKAYGSRKIKKALSKR-----GIQISRRKISRIMKNRGLKSSYTVAYFKVHHSTCNEAKTTNVLNS 6PAX Chain:A ((39-130)) ISRILQVSNGCVSKILGRYYATGSIRPRAIGGSKPRVATPEVVSKIAQYKQE-CPSIFAWEIRDRLLSEGVCTNDNIPSVSSINRVLRNLASE--------------------------

General information: TITO was launched using: RESULT: Template: 6PAX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 96 3406 35.48 48.66 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.60 3D Compatibility (PKB) : 35.48 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.60 QMean score : 0.652

(partial model without unconserved sides chains): PDB file : Tito_6PAX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-6PAX-query.scw PDB file : Tito_Scwrl_6PAX.pdb: