Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTKKIVAIWAQDEEGLIGKENRLPWHLPAELQHFKETTLNHAILMGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQDQEKNLYIIGGKQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTIQYRKRKEV 3TQ8 Chain:A ((3-162)) ----ITLIAAMDKNRLIGRNNELPWHLPADLAHFKSITLGKPIVMGRRTFDSIGKP-LPHRRNIVITQQKNLIIEGCDIFYSLDDALSALT-KEPEVIIIGGARIFKEALPKADKMILTIINHSFEGDVYFPEWNDKE-WKITSQIKHERD--NPYPFQFLELRRLE-

General information: TITO was launched using: RESULT: Template: 3TQ8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 769 -116255 -151.18 -735.79 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : -151.18 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.540

(partial model without unconserved sides chains): PDB file : Tito_3TQ8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3TQ8-query.scw PDB file : Tito_Scwrl_3TQ8.pdb: