Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKQQAKSRKPQQPEYIFQVETLSHEGRGIAHYGSHPDHPADKHGKKVFIRYALPGETVKAQITHEAKRLEEAEMVALLAEPSANRVEAVCPHYGICGGCSMQHIHPDEQIRLKQNVLQSHLQHFAGIQPEQWLEPIRSLQSDYRRRARIGVRYLPKQDRLILGFREHHSNRLTSIHTCSVLDKKLSDSLPELRNLLQSLKGKVHIGHVELAKGDHETSLLVRHIEKLNNADVNQLRQFALHKGWQLYLQPKGPESLRRIDEEQGAMRLHYALNAFDVNFAFSPLDFTQVNATVNEQMVQLACELLQLQQGERVLDLFCGLGNFSLPLARCVGAKGVIVGVEASEEMVQRATDNVKRNNLVQASFFSQDLTKDFSHHSWANQGFDALLIDPPRAGAYEI--IQYVPN-FGAKRIVYVSCNPATLARD-AGVLVQ-HGYQLKK------AAVMDMFTHTEHVESIALFEKIQEIND 1WY7 Chain:C ((48-195)) -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IEGKVVADLGAGTGVLSYGALLLG-A-KEVICVEVDKEAVDVLIENLGEFK-GKFKVFIGDVSEF---NS----RVDIVIMNPPFGSQRKHADRPFLLKAFEISDVVYSIHLAKPEVRRFIEKFSWEHGFVVTHRLTTKIEIP------RKKLERITV---------

General information: TITO was launched using: RESULT: Template: 1WY7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 583 -56754 -97.35 -433.24 target 2D structure prediction score : 0.44 Monomeric hydrophicity matching model chain C : 0.60 3D Compatibility (PKB) : -97.35 2D Compatibility (Sec. Struct. Predict.) : 0.44 1D Compatibility (Hydrophobicity) : 0.60 QMean score : 0.413

(partial model without unconserved sides chains): PDB file : Tito_1WY7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1WY7-query.scw PDB file : Tito_Scwrl_1WY7.pdb: