Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSSLSQVNADVLKQAQQRIQQDLLTTLAAFSIPEPLKSAVHHAVMLGGKRVRPALCYATASLQDNPNFAAARRAAVAVELIHCYSLAHDDLPCMDNDLLRRGQPTCHVAFGEDTALLAGDILQSMAFEVLGSRLFDE--QGQGTDAAIVLKQIQILATAS--SKMVCGQVLDLQAEAKQISQDELENIHRNKTGALIQAAIMMGAVTIFPGTDQAIPKLRQYGQAIGLAFQVQDDILDITSSTETLGKTAGKDEQVQKSTYPALMGLEQAQIYAKELHDQAFEALAHFGE-NAKELVEISQFLLARTN 5XN5 Chain:A ((4-305)) ------DFNAYMGEKAAAVNRALDASIPADEPPAALHEAMRYALLAGGKRVRPALCLAACAVV-GGREAWAMPAAAAVEMVHTMSLVHDDLPCMDDDDLRRGKPTCHVVYGEPIAVLTGDALLSLSFHHMARFDSYPPDIDADKHPARVVRAIGELARCIGSEGLVAGQVVDLEMT---VPLERLEYIHLHKTAALLEASVVIGAIL-GGGSDEQIESLRMYARSIGLLFQVVDDILDVT-----------KDLASDKTTYPKLLGLEKSREFAEKLLSDAREQLSGFDQETAAPLLHLANYIAYRQN

General information: TITO was launched using: RESULT: Template: 5XN5.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1417 -78994 -55.75 -281.12 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain A : 0.79 3D Compatibility (PKB) : -55.75 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.546

(partial model without unconserved sides chains): PDB file : Tito_5XN5.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5XN5-query.scw PDB file : Tito_Scwrl_5XN5.pdb: