Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNNERIYQVLKGLVFSEKAQVLGDTAGVQVFKVDINATKLEIKKAVEKLFGVEVVKVNTTITKGKTKRFGRTLGRRSDVKKAYVTLKAGQDVEMADLGDTAESAAE 5DM6 Chain:Q ((2-92)) ----SHYDILQAPVISEKAYSAME-RGVYSFWVSPKATKTEIKDAIQQAFGVRVIGISTMNVPGKRKRVGRFIGQRNDRKKAIVRLAEGQSIEALA----------

General information: TITO was launched using: RESULT: Template: 5DM6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain Q - contact count / total energy / energy per contact / energy per residue : 332 -32395 -97.57 -355.98 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain Q : 0.77 3D Compatibility (PKB) : -97.57 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.722

(partial model without unconserved sides chains): PDB file : Tito_5DM6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5DM6-query.scw PDB file : Tito_Scwrl_5DM6.pdb: