Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MITVVIIDDDPFVTKSLQTILESTKEIRVLGIGHCAKDALVLYETHRPDVLLTDIRMPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYLIKQN-LQAIIPSVKSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKEVAAGKNNKEIADALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ 5HEV Chain:B ((1-205)) MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAMALRPDVILMDLVMEEMDGIESTKAILKDWPKAKIIIVTSFIDDEKVYPAIEAGAAGYLLKTSTAHEIADAIRATQRGERVLEPEVTTKMME--KMSRRNDPVLHEELTNRENEILMLISEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFK---

General information: TITO was launched using: RESULT: Template: 5HEV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 887 -83696 -94.36 -410.27 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain B : 0.77 3D Compatibility (PKB) : -94.36 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.698

(partial model without unconserved sides chains): PDB file : Tito_5HEV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5HEV-query.scw PDB file : Tito_Scwrl_5HEV.pdb: