Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MALLPILSFPDPRLRTIAKPVEE---VTDEIRQLAADMFETMYAAPGIGLAASQVDRHIQLIVMDLSESKDEPM-------VFINPKVTPLTEETQPYEEGCLSVPQIYDKVDRPSRVKIEAINLEGQAFEIEADGLLAVCIQHEMDHLNGKLFVDYLSPLKRQRVREKVEKIVRQREREKVAVKR 1Y6H Chain:A ((5-161)) -----ILRMGDPILRKISEPVTEDEIQTKEFKKLIRDMFDTMRHAEGVGLAAPQIGILKQIVVVGSEDNERYPGTPDVPERIILNPVITPLTKDTSGFWEGCLSVPGMRGYVERPNQIRMQWMDEKGNQFDETIDGYKAIVYQHECDHLQGILYVDRLKDTK------------------------

General information: TITO was launched using: RESULT: Template: 1Y6H.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 695 19662 28.29 133.75 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain A : 0.77 3D Compatibility (PKB) : 28.29 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.494

(partial model without unconserved sides chains): PDB file : Tito_1Y6H.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1Y6H-query.scw PDB file : Tito_Scwrl_1Y6H.pdb: