Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDEVINVISKCITQLNLFVDGPAAHLSGTAAPTTIETIRKCIADHAYLFTDHRINGQRMWELVCSATFTVGEPRTPTTAATATATLLSLFRRLTDSVAASARAPEADILKHLVKLLRDAVKPPLVRGASPGQLRCLFQAAMRLLKLLLPLKKRADVQTECLHLLLALMQLSDLQEAHCAVVASGDEVAQVAKLCADICGAKHDVALRPQNASMQLLGCLCEQPAYVHALSGQLAERILKCFLDVARNLAQRAEVNQTLGEGLLRGLAGVLGSFPLRCEEDAPALTLINNIVLSALMLGETSTNYTFCLSALFLLRRRASDTLAPFTLLCAAEYSVALRSLWMHRNKDVRRETHAAAAVFWSALSSQLQQRCSSEVADANTTRNTAASHKLHSIVEFLLRSLDSSADPEASYALEALYHLLPAVAALSGPQALQTMSTRLEERVGGLLITASAQRTEALFQQVPYLLATLGQLLTLLPSVSPRQQAVVRELLDWVLLLYPHPKFYNREKTVPGIVLVIRALTHHPRAPHNTLPRLLSERTLELVGEAPGAAMMRLAGERISTEERLDRMATLWTRLLTTREESGAEAEAESKQRLSAAFYRACTGFCERARLEVIVKSNSEATLERILVDGVDGVQPSFPTHYSAFLSFVDFFVRLSEGLKGSGGVCRPPAEELTAWLEALVRGASAALHVSGFYTLLHRTVVGVEGVCPHSLTHQRPYTDASLASGNSDVTSDGHHENHLCVSPLLRHFLSTECLRRVHVYSDELLYQCAMCVVVGAALVGSEDRGELAGSRARACDDHRRLDAYVRAFKVVMTATPTSLQAESVAGSTNEVVCSFGSSPAILESNRQHALRVLEKKACRSPRWAAAVLPALTSALRSAEVVAAVRAPVQMLAARHGVAIAAELQHHSNEATFALLCRGEPASNGRRDSMPRWLATMQPVTVPLVPVDSALHIGYLVPLVSRLSLYGKHPAVRTAAAEVLYWCVVWVIGKKVNDWGSAVFPPLLSLASLARTSTGGSGGGGGSMVHQELHGLLMQAARWFGRSAGTPEEAELFVSVLLRGLGEREGTQRQVATEALFAYAIPPADEPQTVTPHFRAVIGRLVRMECGVSEWSRLGAAHCLHVMMRRLCKVRVPGLVCTVQAVAQGAVGCLRRCTEAPIWGAMETATCNEVQESLRWLGAYCHDIRQLENEEEQREADRFAADLVHAARAVLPALARRHTVCAITLLQTLPAVTHTNASARQVLLLSQELICEQQQRLGPAAVRSLDSTVGGCATLVALLQSGYGTETNKRAIAEAVTPVICTRADDCSVETELLRLLTVVLQAIVEEARVATHESRCISPHIVRWLLELVDVVPEQTHATHFSLLLTPTVIAQAARVMVAGAKVTVENCAGDVGEDATAGVPLRRCAPSSQLAPTARWCLELIEFLMRVAGQRRRGAQVIEDVLCAIRETSVFTVFTAASPARQLIDALSVGPSALVTGPVALAAALCQMEAPCSSGTTTLWMRIADSMKISPKTVVAMLLGLLRNSAALNATGGEEVCEGLLVLMLSEPDPALLRQHLRDLLASDAVQHNIFTSSSFAVSLEDGHGAVAVSPSSRSTSVLLSRAFDSVMNRCWQQASAALPTDRLVSALPSLTTVAMSEDALRSSSEAVSLFSLVGDWLAELQRRSLTSEHDKVLCRVCANLVAAEREMRQSTPTAAQDDGRGGARLAALLMLVQLIGPAIRTDTTLSSALCDLVLFVSKPANMCSLLASVDATEHVVWGFHVLAATMTPRPARRSLAVFPVDLRAVEMAFDFLNEVLNSALPLRWTELKTPREKTNGADVVRSGTALFAAVLPHKVQVLEVIAPLLAQESMPQRDTIVRQVHGALQALSVCQQALQLDACRCASRLLRDPRTHPGICDALTEHVLLPLLQASAEAVRLRLFEEEVRNWVTEAGRAPALGCFYMQTAAFSCLALMHRLCPLTELRGSISTAFTGRNPNTTGVELTLEVLKACRAAWQSPNTGGDDNSAEEADGDVGDSACADAPRRYRQAAFRCLLATLSQTQQAEKVFCRCFFQERSVAGWNGLFLVKRPGVAVTDLLDAVGEVQLWRDMDRCQVPELFAHLLRHFPSSSVTPGEPPEWVRHVVAVLRQPQLRLPVRMVFYEMICRHERFFGTFARCIFDGVADAVAAMAPSERAGKVIWELLALLTRWHREGSSRALAVGSAASLKALARYAAVHLAWEHSFTACEGSRALDPTSHKRLAELLEQFRRAQGAALAIRSTSQPLTAAEMKMLLSHPAYERHAALEVIYLITNACGCLGCTGDSREVVEVYDLLGAFLGASASPQLYHITARLVGLEHRLLSEAATREPSSAVRKLLRDALRGTVCAILSVCKSDKKFLEVLEAMQEDRSGDLVYQLLSRTDLLRRYSIRKDSEKLLTLRVLARAGTYVADNYDSIHVCLSGLLRGGQGEPLLGICTVVKNALPHMSMESVRHVLRDLCCLDVLQAMESAEPARIAFYKMGLAALRRWTVVREDQEKQDGGGSVSADAEAFLVRRGLRDASPAVQGAVLEYLDVHAQHVPDTMWGRLTCLFTAEDGASGDGHSGSGGWVRHVALLLLSLSKRSRDFANPTYFCPEALHSEGASPTLATSADTAAESSVAQRQPRSAPLFSEAVQCGSPAEAATANAACPITAALAQIYVPPALVPQPPHQQQQPLSGARRPRATGAWRLGAAPCAAATAVTRSWLRLESGDSEQENAVISAGVMASRQISATMQRNAAHGAALQAGRSVMNAPSAAPSLESNTAGRLSEVRLTLQSLLVPLQVLCLHEDEVAARVLIDLISNAAVASPVTSESPHIVSLCSALTSLLPKFQSGATTRQCELAKNPFTLFVALELLLHAQAAGWSSLASLDCAALVRLTSDVQAYGGSVPTAFLPVVDGTAHVVEKLLSSLQPSAARGVPTRPSLEFPALGWHAYHVAQRLRRHDDAACQAALQLFRATRRHEAPVIQLQGALDAMEVGGAAYSMRVIAKLLEDEEKEAAAAVATVASPATHVSGGAFALFAAREEVLRHYRSRASRLLLDWCGAASALQSATPVGAGGSGEVSVEGVRLRLRAQLQLMCNGAASAVTAEASTASRHRTGFEWGACLMANGRWLDCQLHAETSVDHLLESTASHYDSGGSSLVCGYLAANSLSQLADAAQVLRFVSTSAASSAGVALQTYLDTMPALVPLSGAYGSLFIDDVLLIRRLIIDYHVQSTGDLLGSLQFTDNERHKLVAQIHELLGTWTVQQCSELLLLPEKTSAIETIASKADHATLSEPTRCALELLKKRSSLFSIAVTPREASGASREEALAAFQKATGKDVQQRAAAGLLSPAAARQWAADVAQCEVEIFASIGSILSIPAGSAASVQKREIWVSTLKENLRDTIPSHVALLNALEKLLPPVSRGDGTLADMGGDAKDAARASYITAATQSLWQLYANTFLWCAQAVGDRSMQVGSGGHLPVSARVPRLLSL-FALPRVAEAAAQAQWRGTWEALVMLPTLVWLPWATLLVNALLQTEHAVLARILLRLCRERG----QVLYYPINCAWRSLADLGKRRNAGRAVDDDLTRELAELHKWHRSHRMALVAEFAAALDELVEPQHRLEVRLSEV--ESLVKQHEQCTRGGGGA-QAEYLMAALQ-LYERCKSDLMDPARWGRAQLYHRRAAQVLQELDRRNAFSAEVLKSGEQFRSAKR----EALRQVAQTLSTLSTSASNSATRSQELRLYSERLQHALGRSATAATTTTTQLGYTSDAAEPILQPVQPTHLLHTPPDAAQQCCTLVGVADRVLVLKSKRLPKKVDIYTSAGI-CTYMVKGGEDLRLDQRIQEVFTFANLCLLVSPRSRLSALTIRTYAVVPVSPLVGLICWVPRTTPLQELMKE-----ATPPDAHDAVARFCRARGKPQEILPLYKTAHITGIPEQEYKDLVYCLRQSA---LVESLQSIATDHCSWLGARDAFLDTNAAASMASFVLGVGDRHAGNLLVDLLNSELVAIGFGLAFGDATRKLPVLELMPFRHTPQL---QRVQGVLGDDVTRCRMRHVLHVLRAERQVVEGMVAALLMPDADAIGDEESRIAGHQLDVVRRKLNLEHPAGIILRDVARNAYVTQDKDVWIGVKACLCERKRDENGEDADLTETALSALHQEDVFVQRLLRIASDPRVLGRAYAGWQAYM 5FVM Chain:A ((1843-2359)) --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLLTLWFKFGGIPEAA-----QAMHEGFGLIKIDNWLEVIPQLISRIHQPNQTV-SRSLLSLLADLGKAHPQALVYPLTVAIKS--DSVSRQRAALSIIDKM-----------RMHSPKLVNQAELVSDELI----RVAVLWHELWYEGL----EDASRQFFGEHNTEKMFATLEPLHEMLK-----------------RGPETLREISFQNSFGRDLNDAYEWVLNYKRTKDINNLNQAWDIYYNVFRRISRKLPQLQTLDL-----QH-VSPKLSAAKDLELAVPGTYHAGKPIVR------ITHFEP--------------VFTVISSKQRPRRVIIKGSDGKDYQYLLKSHEDIRQDNLVMQLFGLVNTLLQNDPESFQRHLNIQQYPAIPLSPKTGLLGWVPNSDTFHVLIREHREASKIPLNIEHRIML---------QMAPDYDNLTLL----QKVEVFTYALDNTKGQDLYKVLWLKSRSSESWLDRRTTYTRSLAVMSMVGYILGLGDRHPSNLMLDRITGKVVHIDFGDCFEAAILREKYPEKVPFRLTRMLTYAMEVSGIEGSFRITC--ENVMMVLRDNKESLMAILEAF-----------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 5FVM.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2160 30413 14.08 61.81 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.52 3D Compatibility (PKB) : 14.08 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.52 QMean score : 0.313

(partial model without unconserved sides chains): PDB file : Tito_5FVM.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5FVM-query.scw PDB file : Tito_Scwrl_5FVM.pdb: