Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFDMRLSHERGAAHHGWLQSKHTFSFANYWDPKQVGFSDLLVINDDTVAPSKGFGTHPHRNMEIISYVLEGALEHKDSMGTGSVIVPGDIQLMSAGRGVAHSEFNHSAQENVHFLQIWVVPNEVNTTPGYQQLHISEEDKCGKLHLMISPKGG-EKTLSIKQDINIYSGLFDGEETA-EFAIPEGRYVYLHVAKGHIDVN-----GKTFNTGDAARIRDGGKLSFTNGDNAEILIFDMRPEEIPTMP 2VEC Chain:A ((30-256)) ------ARQCGQADYGWLQARYTFSFGHYFDPKLLGYASLRVLNQEVLAPGAAFQPRTYPKVDILNVILDGEAEYRDSEGNHVQASAGEALLLSTQPGVSYSEHNLSKDKPLTRMQLWLDACPQRENPLIQKLALN----MGKQQLIASP-EGAMGSLQLRQQVWLHHIVLDK-GESANFQLH-GPRAYLQSIHGKFHALTHHEEKAALTCGDGAFIRDEANITLVADSPLRALLIDLPV-------

General information: TITO was launched using: RESULT: Template: 2VEC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1147 -39409 -34.36 -179.13 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : -34.36 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.461

(partial model without unconserved sides chains): PDB file : Tito_2VEC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2VEC-query.scw PDB file : Tito_Scwrl_2VEC.pdb: