Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGQLTDASVVLRFGYQAIRRAGLPTEEILTKAGVALNQVDTNARTPLSAQYAFWTAAQEVSKDPDIGLHLGEHLPLYRGQVIEHLFNSSETFGEGLKRALAY-QRLISDAFDAKLVVEDG---RCYLTNGEQVGADNLVNRHFSECAISGVLRFFKFITEGQFHPIFIDFNFSEGASEDEYFRVYGCPVSLGQKETRLYFDPAILDFQLWQAEPELLQLHEQLA-IEKLQELARY-DLVGEVRRAIGSTLESGETTLETVAAQLNITPRRLRTQLSEANTSFQQILSDYRCRLAKKLLANTNESVERIVYLTGFSEPSTFYRAFKRWTNETPVEYRKRKQHR 5CHH Chain:A ((4-328)) --------ENIQYDFE-----WRPLNNYLAVQRI------TPPRLPSEALYEWIVLN---GRSPLEGLSLGEHYRLSDYGVAGLALQSAGTVGEALQLIKTNMLLFRKDIRGIAVRRSSCDTVDVDIDLQDKPDWPQSARLYHANVLASAAYAVFRDLLLGELELVRLRLP-ERNGDVRAYEEYFRVPVYFAGAGITFTLPEELLEAEIATANSAVFQASLALGSKAFNTRVTREMGGYRQRIVALLEVLQDRYPSIAWVARQLKVTERTLRRRLADEGTNYREVLDLVRHDRARQLLRDERLRIEEVAERLGYMDTSSFRHAFRRWTGQCANDYRQA----

General information: TITO was launched using: RESULT: Template: 5CHH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1368 5367 3.92 17.37 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : 3.92 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.403

(partial model without unconserved sides chains): PDB file : Tito_5CHH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5CHH-query.scw PDB file : Tito_Scwrl_5CHH.pdb: