Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFKGPDMQAIILDTETHTLNGLPIEIAYAPIEINAGKLTLDKSKLFDQLYQVGTPISYAAMAVHHILESDLENQPHYKTFKLPD--TTTYIIGHNIDYDIAAIARCGVDVSHIKPICTLALTRKTWPDAEAHNISALIYMISQGSSKARELLKGAHRADADIILTANILMHIVYHLNIHDIEELYRVSEEARIPTTINFGKHKGTAIAELPKDYIQWLLRQDELDVYLRKALESAF 4FZX Chain:C ((4-150)) ----------IIDTETCGLQGGIVEIAS--VDVIDGKIVNPMSHLV----RPDRPISPQAMAIHRITEAMVADKPWIEDV-IPHYYGSEWYVAHNASFDRRVLPEMPGEW-----ICTMKLARRLWPGIKYSNMA--LYKTRKLNVQTPPGLH-HHRALYDCYITAALLIDI----------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 4FZX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 702 -52839 -75.27 -364.41 target 2D structure prediction score : 0.50 Monomeric hydrophicity matching model chain C : 0.69 3D Compatibility (PKB) : -75.27 2D Compatibility (Sec. Struct. Predict.) : 0.50 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.280

(partial model without unconserved sides chains): PDB file : Tito_4FZX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4FZX-query.scw PDB file : Tito_Scwrl_4FZX.pdb: