Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSTESASGTPTQPSL-FVLVKQILILAGFWWIGYLLHQKLGVP-VSAGILGMFLLLLCLFFKIIKMDQVAMG-ATV-VLGELLLFFVPVVVAVVQYKTLFMTEGWQ---------IVLSIAVGTILVMLSTSLTIHYYNRLKAYLQARKRLQHKHI 3V7B Chain:A ((5-151)) ---VHDSALPFDALPMPPQGREGFEECPYL-DSQWVADTNGQRMTGQGVDTRFDTPACVFWSYPEAPQATV-MVRHMPSEEEAIRVVDWAAPIDTTEPAEEPDGWSGGRAGHEEGAVYAVQKGPVAVVVWSNQQ----QSLKAELMAKEAIARLGL

General information: TITO was launched using: RESULT: Template: 3V7B.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 694 -38937 -56.11 -290.57 target 2D structure prediction score : 0.46 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : -56.11 2D Compatibility (Sec. Struct. Predict.) : 0.46 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.278

(partial model without unconserved sides chains): PDB file : Tito_3V7B.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3V7B-query.scw PDB file : Tito_Scwrl_3V7B.pdb: