Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MARMAKVVELPSIAKIDKSKGKISAQLTQALREAVQSGDLQPGDPLPSSRELALTLGVARGTIIEAYDQLLAEGVFDSQPRTGTYVSHALVKTSAIQHSSKENKPNSISLNKSARSYAKVLDEFKPLPHVPFAVSVPIARTQ------PSDIWRKFGNKFRSRGAGVPSGYGEPQGVLSLRIAIADYVRRSRSVHCEPEQIVITPSIQQSLYICNQILFEAKDEVW-VEDPAYRGTTAIFEHTVQNIRMVRVPVDEEGIQIETGIKLSKQASAAFVTPSHQYPLGMPMSLARRTALLAWAKQQ-NAWIIEDDYDSELRYNGQPFPSLQGMAPDQ-AIYLGTFSKVLFPSLRLGYAVLPKELVAPFCGLRVLIDRHPPAADQHVLAAFIQEGYLERHIRRTRNVYAEVREYIIGLIEKYIPQELAWLQLGDQGMHMVLWLAQHINDIDVASSAVDAGIAIKAISPTFSKERRRS----GLIVGLGDFEPELMQQAIKKLSKIIQQHAKSM 4N0B Chain:A ((16-473)) ----------------------IYQQIYQKLKKEILSRNLLPHSKVPSKRELAENLKVSVNSVNSAYQQLLAEGYLYAIERKGFFVEELDM------FSAEEHPPFALP------------DDLKEI-HIDQSDWISFSHMSSDTDHFPIKSWFRCEQKAASRSYRTLGDMSHPQGIYEVRAAITRLISLTRGVKCRPEQMIIGAGTQVLMQLLTELL--PKEAVYAMEEPGYRRMYQLLKNAGKQVKTIM--LDEKGMSIAEITR--QQPDVLVTTPSHQFPSGTIMPVSRRIQLLNWAAEEPRRYIIEDDYDSEFTYDVDSIPALQSLDRFQNVIYMGTFSKSLLPGLRISYMVLPPELLRAY-KQRGYDLQTCSSLTQLTLQEFIESGEYQKHIKKMKQHYKEKRERLITALEAEFSGEVT-VKGANAGLHFVTEFDTRRTEQDILSHAAGLQLEIFGMSRFNLKE----TGRPALIIGFARLKEEDIQEGVQRLFKAVYGHKK--

General information: TITO was launched using: RESULT: Template: 4N0B.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2115 -1514 -0.72 -3.43 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : -0.72 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.486

(partial model without unconserved sides chains): PDB file : Tito_4N0B.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4N0B-query.scw PDB file : Tito_Scwrl_4N0B.pdb: