Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNSRVQVSYQPIIDIEFSGLHLIEASAGTGKTYTLSSLMVRIFLEKYLPGQVIATTFTRAAAAELKSRIRARLVETHRYLDAKRSLTEKEILLQAEQESDLLLQHILKHFATRIAYACERLKLVIDQLDELFVGTLDSFSQKLLREFAFESGKIERAQITDDAKTYSRQLIHDVLREWIQSQPQTVIDALYLAGELKSVDSFVKLVEDSLNFSSAHFKLPEKPTIQFEQLAQLKQLAAEIDISLLEPYYSLDGDHYKHVSGTIFRNGAFNKLFSECLPQLLQVLKQSDSILVFDGSLAVQRELVFKFLGQLADQKVFKKCPAEISDGFYQHPCIQQIQQLFGVLKNYAEQFDQLHIYLKAYFCVEVKKRLPQVLQNKGETTFSQQIRTLSEALKGEQGQRFAVFVQARYPLILVDEFQDTNQDQDDMLASIWRH-PERYQKGCMIMVGDRKQAIYGFRGGDMLTFLNAYKDIQAKHGREYKLIHNHRSVADLVEVVDALFQRQID--FGEQVQYDPIRAGTRPHPV-LIDQNQPNPHPLRWLMLKD-------KETEAQQVAWKIRDLLNQSHAGQLYFQKDAQTQTLNEDDIAVLSRNHDGLDKVQFELERLGI-RVNRPSKRSVFDCTIAQDVGALLTAIFHPYDEAKVKRALISRLFAMDLKQLLQLEQTAEGLSQFMTGFDTIRELWSAQGFLVAWQQCLNQFGIWKNLVAVQSKDNERVVVNLRHLTEILSQHSEKYQGAQNLYHWYLKQLQSPLDREWELERRLSSEAG-VQLMTIHQSKGLEFKIVFLLGADTPFRENNKTLNFSTQDITVSESAQTLTQRVVAIADKTYLNETELKQHEERALAEQNRLWYVALTRA----SHRVYALLQ-------DTDGKSVSGLAFWKNRAEPFQ----HRC----CTDEIILEQPPAARHLNQHINII---EIQA---QHFPDQRFYSRGKTSFSYLAQHLRHKVGTDLLASQSHEAVLAEDELDQVISVETATAQPISWIKSNFPRGTLAGNFLHEIFEHIDFQ--CSDEWVSEIRRRFKNDYSSLWQDLLIKYQESFPEEQEAEYSLYHAVAEWLQEILSTPLYQ-GFRLNQLQPEHYLSECPFYLALSDRVLA--MKRIQQLFAEYGMEMPELLEARSARYLNGSIDLVYFDGQRYHIADYKSNYLGENLADYSVESIAQSMALASYWLQAGLYLVALHRYLKVKMQNYDIEQHLGGATYLYLRGMNGE-AEQGYYYWQPSTEFVLRLDAILGYFAEDKIA 3K70 Chain:B ((306-1173)) -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHPLFEAIDQLL------AEPLSIRDLVITRALA-EIRETVAREKRRRGELGFDDMLSRLDSALRSESGEVLAAAIRTRFPVAMIDEFQDTDPQQYRIFRRIWHHQPE----TALLLIGDPKQAIYAFRGADIFTYMKARSEVHA----HYTLDTNWRSAPGMVNSVNKLFSQTDDAFMFREIPFIPVKSAGKNQALRFVFKGETQPAMKMWLMEGESCGVGDYQSTMAQVCAAQIRDWLQAGQRGEALLMNGDDARPVRASDISVLVRSRQEAAQVRDALTLLEIPSVYLSNRDSVFETLEAQEMLWLLQAVMTPERENTLRSALATSMMGLNALDIETLNNDEHAWDVVVEEFDGYRQIWRKRGVMPMLRALMSARNIAENLLA--TAGGERRLTDILHISELLQEAGTQLESEHALVRWLSQHILEPDSNASSQQMRLESDKHLVQIVTIHKSKGLEYPLVWL-----PF-----ITNFRVQEQAFYHDRHSFE----AVLDLNAAPESVDLAEAER-LAEDLRLLYVALTRSVWHCSLGVAPLVRRRGDKKGDTDVHQ-SALGRLLQKGEPQDAAGLRTCIEALCDDDIAWQTAQTGDNQPWQVNDVSTAELNAKTLQRLPGDNWRV---TSYSGLQQR-GHGIAQDLMPR------LDVDAAGVASVVEEPTLTP-----HQFPRGASPGTFLHSLFEDLDFTQPVDPNWVRE--KLELGGFESQWEPVL---------------------TEWITAVLQAPLNETGVSLSQLSARNKQVEMEFYLPISEPLIASQLDTLIRQFDPLSAGCPPLEFMQVRGMLKGFIDLVFRHEGRYYLLDYKSNWLGEDSSAYTQQAMAAAMQAHRYDLQYQLYTLALHRYLRHRIADYDYEHHFGGVIYLFLRGVDKEHPQQGIYTTRPNAGLIALMDEMFA--------

General information: TITO was launched using: RESULT: Template: 3K70.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 3424 29820 8.71 36.19 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain B : 0.69 3D Compatibility (PKB) : 8.71 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.364

(partial model without unconserved sides chains): PDB file : Tito_3K70.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3K70-query.scw PDB file : Tito_Scwrl_3K70.pdb: