Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRQQSEHHYAEHNDHHHGHHRSGRRGRLFEAGRMKLLVLHLIQQSPKHGYEIIKEISDLVGDGYTPSAGTIYPTLTSLEEMNLINLL-D---VERKQYQITEFGEAYLNEHQDKLSGLLEKLRLRREIHSNDQLIEIHRAMENLKTALRLKLNTTDLKQEQIYQIAEKIDQAAVAIGRL 1XMA Chain:B ((34-135)) -------------------------SSDVIRGYVDTIILSLLIEGDSYGYEISKNIRIKTDELYVIKETTLYSAFARLEKNGYIKSYYGEET-RRTYYRITPEGIKYYKQKCEEWELTKKVINKF------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 1XMA.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 294 -32442 -110.35 -341.49 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain B : 0.68 3D Compatibility (PKB) : -110.35 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.548

(partial model without unconserved sides chains): PDB file : Tito_1XMA.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1XMA-query.scw PDB file : Tito_Scwrl_1XMA.pdb: