Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MISTHILDTNLGKPAAQVEVKLFHTATHELIATAITNQDGRVIDFGIKNLGKDAYQLEFEVAPYFSSQQIKTFFPRVCIQFFIEDTNQHYHIPLLISPFAYSTYRGS 3QVA Chain:A ((12-116)) -LSTHILDISTGTPAEGVTVSLSRE--GETLANLVTNAQGRIATFSAAPLPAGRYCLTAETGAWFARAGRESVFTRAQIDFVI----DHFHLPFLIAPGGWSTYRGS

General information: TITO was launched using: RESULT: Template: 3QVA.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 472 -71001 -150.42 -710.01 target 2D structure prediction score : 0.42 Monomeric hydrophicity matching model chain A : 0.81 3D Compatibility (PKB) : -150.42 2D Compatibility (Sec. Struct. Predict.) : 0.42 1D Compatibility (Hydrophobicity) : 0.81 QMean score : 0.451

(partial model without unconserved sides chains): PDB file : Tito_3QVA.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3QVA-query.scw PDB file : Tito_Scwrl_3QVA.pdb: