Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTTQNLMCPVCRQRLELVSKTWRCEQGHSYDIAKQGYVNLHVVQHKHSKNPGDTPESVDARRAFLQGGYYQPLQQAVVHLLK---DLQAKMVLDIGCGEGYYTSAMQQVVEQ--CIGVDIAKNAVQRAAKLNDKVTWVVGTGATLPVIDQSMDVCTSLFSPIPQTEILRVVKDDGYLIVVTSATDHLYAMREALFEQVNPHIPQKFVEQLQDLFELKEQQVIDAPLVLDQQALKNLIAMTPYAYKASPERRMQLEQKAHLQVTASFQIYLFQKRNKKAI 1P91 Chain:A ((2-267)) ----SFSCPLCHQPLSREKNSYICPQRHQFDMAKEGYVNLLPVQHKRSRDPGDSAEMMQARRAFLDAGHYQPLRDAIVAQLRERLDDKATAVLDIGCGEGYYTHAFADALPEITTFGLDVSKVAIKAAAKRYPQVTFCVASSHRLPFSDTSMDAIIRIYAPCKAEELARVVKPGGWVITATPGPRHLMELKGLIYNEVHLHAPH--AEQLEG-FTLQQSAELCYPMRLRGDEAVALLQMTPFAWRAKPEVWQTLAAKEVFDCQTDFNIHLWQR------

General information: TITO was launched using: RESULT: Template: 1P91.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1252 -54898 -43.85 -210.34 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.80 3D Compatibility (PKB) : -43.85 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.80 QMean score : 0.453

(partial model without unconserved sides chains): PDB file : Tito_1P91.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1P91-query.scw PDB file : Tito_Scwrl_1P91.pdb: