Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAERLNNDFQFLDVPRQDPEKKDITVRKAEFVEIYKPFTSETVTNQTHRCLGCGNPYCEWKCPVHNYIPNWLKLIAEGQIFQAAELCHQTNTLPEVCGRVCPQDRLCEGACTLND-GFGAVTIGNAEKYINDTAFALGWRPDMSHVKWTGKKVAIIGAGPAGLGCADILARGGVKPVVFDKRPEIGGLLTFGIPEFKMEKDVMKRRREIFTGMGIEFRLNTEIGKDVTIDELLAEYDAVFMGMGTYTYMKGGFPGEDLDGVYDALDFLISNVNRCQGW--EKDPSEYISMDGKKVIVLGGGDTAMDCNRTSLRQGAHDVTCAYRRDESNMPGSAREVKNAYEEGVKFLFNRQPIEIVGENGKVTGVKVVTTQMGEPDSRGRRSPEPIPGSEEVLPADAVLLAFGFRPSPAD-WFGSVNINLDGSGRVVAPEQQEFKFQTSNPKIFAGGDMVRGSDLVVTAIWEGRQAAEGILDYLGV 2VDC Chain:K ((1-444)) ----------------------------QDFAEIYARFSDERANEQANRCSQCGVPFCQVHCPVSNNIPDWLKLTSEGRLEEAYEVSQATNNFPEICGRICPQDRLCEGNCVIEQSTHGAVTIGSVEKYINDTAWDQGWVKPRTPSRELGLSVGVIGAGPAGLAAAEELRAKGYEVHVYDRYDRMGGLLVYGIPGFKLEKSVVERRVKLLADAGVIYHPNFEVGRDASLPELRRKHVAVLVATGVYKARDIKAPGSGLGNIVAALDYLTTSNKVSLGDTVEAYENGSLNAAGKHVVVLGGGDTAMDCVRTAIRQGATSVKCLYRRDRKNMPGSQREVAHAEEEGVEFIWQAAPEGFTGD-TVVTGVRAVRIHLGVADATGRQTPQVIEGSEFTVQADLVIKALGFEPEDLPNAFDEPELKVTRWGTLLVDHR---TKMTNMDGVFAAGDIVRGASLVVWAIRDGRDAAEGIHAYAK-

General information: TITO was launched using: RESULT: Template: 2VDC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain K - contact count / total energy / energy per contact / energy per residue : 2698 7178 2.66 16.31 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain K : 0.79 3D Compatibility (PKB) : 2.66 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.362

(partial model without unconserved sides chains): PDB file : Tito_2VDC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2VDC-query.scw PDB file : Tito_Scwrl_2VDC.pdb: