Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSDRIREK------LQILADAAKYDVSCSSSGSDRKNKNKGLGDASHSGICHSYTEDGRCVSLLKILFSNVCIFDCAYCVSRRS--NDVQRAAFTVQEVVDLTINFYRRNYIEGLFLSSGIFKSADHTMER-MLQVVKK--LRLEENFNGYIHLKTIPGASPELIHEAGLYADRMSINLEMPTEIGLKTFAPEKSHQEVQKDLGLVR-DRLIQLKDERQIIKHVPKYVPAGQTTQMVVGAHQESDQDVLFMADKHYKEFKLKRVYFSGYIPINNENNYLPAVGSAPPLLRENRLYQSDWLMRFYGFEVNEIVNEKHPNLDLDVDPKLSWALRHPEQFPVDLNRADYQMILRVPGIGVKSAKKIVQARRFGKIHIDLLKKLGVA---YQRAKFFIRCEDSPKFQKELSSSFIRQQILTQGSSKYVQQLSPQLSLGF- 1ZY7 Chain:A ((8-402)) SRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTGTDVKDAKVISVSTGTKCI-NGEYMSDRGLALNDCH------------AEIISRRSLLRFLYTQLELYLNNKDDQKRSIFQKSERGGFRLKENVQFHLYISTSPCGDARIFKARG--------QLRTKIESGEGT-IPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAMYQRI--------SNIEDLPPLYTLNKPLLSG-------------------ISNAEARQPGKAPNFSVNWTVGDSAIEVINATTGKDE--LGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKL--AAKEYQAAKARLFTAFIKA-----GLGAWVEKPTEQDQFSLT

General information: TITO was launched using: RESULT: Template: 1ZY7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2073 56711 27.36 156.66 target 2D structure prediction score : 0.44 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : 27.36 2D Compatibility (Sec. Struct. Predict.) : 0.44 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.128

(partial model without unconserved sides chains): PDB file : Tito_1ZY7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1ZY7-query.scw PDB file : Tito_Scwrl_1ZY7.pdb: