Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTEGVGLPLWLLAELT-YRCLLQCPYC------SNPLDYAQHKNELTTQEWFDVFDQARQMGAVQLGFSGGEPLV--RQDLEQLVAHAHQLG-----FYTNLVTSGMGLTEQRISHLKQAGLDHIQISFQASDPVLNDAL--AGSKHAFEQKYEMCRLVKKYDYPMVLNFVIHRHNIDQIDKIIELCLELNADTVELAICQFYGWAFLNRQGLLPTQEQLIR-AERITNEYREKLKAQNHPC--KLIFVVPDYYEERPKAC-MNGWGKIFFTVAPDGMALPCHAARQLPISFPNVREQSLSRIWYESTGFNRFRGDAWMPEGCRSCPDKDRDFGGCRCQAYMLTGDASNADPVCGKSPYHQFIEQARAESEIDSSLEKLVFRNSRNSKQFTVQQNIPVQNIVDD 4K36 Chain:A ((2-392)) ------PPLSLLIKPASSGCNLKCTYCFYHSLSDNVKSYGIMRDEVLESMVKRVLNEAN--GHCSFAFQGGEPTLAGLEFFEKLMELQRKHNYKNLKIYNSLQTNGTLIDESWAKFLSENKF-LVGLSMDGPKEIHNLNRKDCCGLDTFSKVERAAELFKKYKVEFNILCVVTSNTARHVNKVYKYFKEKDFKFLQFINCLDPLYEEKGKYNYSLKPKDYTKFLKNLFDFWYEDFLNGNRVSIRYFDGLLETILLGKSSSCGMNGTCTCQFVVESDGSVYPCDFYVLDKWRLGNIQDMTMKELFETNKNHEFIKLSFKVHEECKKCKWFRLCKGGCRRCRDSKEDSALELNYYC--QSYKEFFEYAFPRLINVANN----IVDKLAAALEHHHHHH--------

General information: TITO was launched using: RESULT: Template: 4K36.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1915 -2176 -1.14 -6.03 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -1.14 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.358

(partial model without unconserved sides chains): PDB file : Tito_4K36.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4K36-query.scw PDB file : Tito_Scwrl_4K36.pdb: