Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFDLIIIGAGTAGISAYKEAVKYTNNLLIINDGPWDTTCARVGCMPSKVLISTANRMYDIQNAQEVGLSA-SADISTDQVMEHVRTLRDRFTKATVKDVEQWPTEHKISGKAHFIDAKTIEV-NGKRHQSKSFILAVGSTPNYDQTWKQELDDRLITTDQIFELNTLPKSIAIIGSGVIALEIAQAMHRLGVETTIFARSKRIGIFTSPKLQQLAQEELSKELNFLFETLPHEVKS--TSDGVILNYKI-NEKEESIQTEYVLSATGRSSLLDTLKLENIDKSFKDIKLLPVNAKTKQLDNYPIFIAGDAYTSTPLQHEAAHEGKKVVHNCLNYPQL-NSVKTLPPLGIVFSHPEMAIVGQSYKQLKDDG-----VDFVTGEASYERQGRAIVLGKNKGAIEVYIERESQKLLGAELFTEATEHMAHLLSWIIGEELTLNDILEKPFYHPTLEEGVRTALKHARRQLK 3IC9 Chain:C ((8-471)) NVDVAIIGTGTAGMGAYRAAKKHTDKVVLIEGGAYGTTCARVGCMPSKLLIAAADASYHASQTDLFGIQVDRISVNGKAVMKRIQTERDRFVGFVVESVESFDEQDKIRGFAKFLDEHTLQVDDHSQVIAKRIVIATGSRPNYPEFLA-AAGSRLLTNDNLFELNDLPKSVAVFGPGVIGLELGQALSRLGVIVKVFGRSGSVANLQDEEMKRYAEKTF--NEEFYFDAKARVISTIEKEDAVEVIYFDKSGQKTTESFQYVLAATGRKANVDKLGLENTSIELDKKNSPLFDELTLQTSVDHIFVAGDANNTLTLLHEAADDGKVAGTNAGAYPVIAQGQRRAPL-SVVFTEPQVASVGLSLRQIEDLYADQDAANYVVGQVSFEGQGRSRVMGKNKGLLNVYADRTSGEFLGAEMFGPAAEHIGHLLAWARQQQMTVQAMLTMPFYHPVIEEGLRTALRDAQQKLA

General information: TITO was launched using: RESULT: Template: 3IC9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 2611 21694 8.31 47.89 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain C : 0.81 3D Compatibility (PKB) : 8.31 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.81 QMean score : 0.492

(partial model without unconserved sides chains): PDB file : Tito_3IC9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3IC9-query.scw PDB file : Tito_Scwrl_3IC9.pdb: