Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKIVILNKPYDVLSQFRKDEAHMTVSDFVDDPTLRIAGRLDMDSEGLVFLTDHGGLNQFITNPANKKYKTYLVQVDGDVTEEALEQLRKGVELNDGMTLPAKAIKVSEPEWLWDRDPPVRYRASIPTSWIEISICEGRNRQVRRMTSAVGFPTLRLIRTKIGTIDLVQLGLQPGETKEIEPLLYPDFKDVPAEQPYRSRSYVRKPGGTGGKPMVRKNKDGSAKKSGTKRIWQMDESEKPRRKTNGTTRPNTKAPRGRSRNSR 2OML Chain:A ((11-189)) TRVILFNKPYDVLPQFTDEAGRKTLKEFIPVQGVYAAGRLDRDSEGLLVLTNNGALQARLTQPGKRTGKIYYVQVEGIPTQDALEALRNGVTLNDGPTLPAGAELVDEPAWLWPRNPPIR-RKSIPTSWLKITLYEGRNRQVRRMTAHVGFPTLRLIRYAMGDYSLD--NLANGEWREVTD---------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 2OML.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 870 -77172 -88.70 -433.55 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.79 3D Compatibility (PKB) : -88.70 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.540

(partial model without unconserved sides chains): PDB file : Tito_2OML.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2OML-query.scw PDB file : Tito_Scwrl_2OML.pdb: