Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAKLKTRRGAAKRFKATANGFKRKQAFKRHILTK-------KSAKRIRQLRGCV--------MVHVSDVASVRRMCPYI 2V6Z Chain:M ((25-99)) MAPERLRSRALSAFKL--RGLLLRGEAIKYLTEALQSISELELEDKLEKIINAVEKQPLSSNMIERSVVEAAVQESS--

General information: TITO was launched using: RESULT: Template: 2V6Z.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain M - contact count / total energy / energy per contact / energy per residue : 140 -4262 -30.44 -71.03 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain M : 0.63 3D Compatibility (PKB) : -30.44 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.475

(partial model without unconserved sides chains): PDB file : Tito_2V6Z.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2V6Z-query.scw PDB file : Tito_Scwrl_2V6Z.pdb: