Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLLTVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQ---SRAISVMFSKPNGKTYQDMLDVFNDPELMEEL--NRPIFYYPIVYDVHEL---EQKYNIRTDEVTFIFFDGGKEANRITAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN 2MOD Chain:A ((18-119)) -------------------------------------------------------------------GPGSMIEQIGDSEFDNKVTSCNDNILILVDFWAPWCGPCRSLEPQLE--KLAQQYTENVKIYK----INIEDNQDVATQYGVSA-IPTILMFKNGKKLSQVIGA--DISKI-------------------------------------

General information: TITO was launched using: RESULT: Template: 2MOD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 342 -9448 -27.63 -100.51 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.60 3D Compatibility (PKB) : -27.63 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.60 QMean score : 0.587

(partial model without unconserved sides chains): PDB file : Tito_2MOD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2MOD-query.scw PDB file : Tito_Scwrl_2MOD.pdb: