Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence RPYHGRIQDLRRPLLCDVYIEYPSGQVFDQALGHDIVPAGETAEISGFKCKTVR-GTCVILPTCDTPPEYRVTSWKFEREMSD---PERTRFIARFPNVRI-- 5JA9 Chain:C ((2-109)) KSVFVESTIFEKYR--DEYLSDEEYRLFQAELMLNPKLGDVIQGTGGLRKIRVASGSRIIYYFLDEKRRFYLLTIYGKNEMSDLNANQRKQLMAFMEAWRNEQ

General information: TITO was launched using: RESULT: Template: 5JA9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 367 -38586 -105.14 -406.17 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain C : 0.67 3D Compatibility (PKB) : -105.14 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.345

(partial model without unconserved sides chains): PDB file : Tito_5JA9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5JA9-query.scw PDB file : Tito_Scwrl_5JA9.pdb: