Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQMEMQLMAFELVDLDRQGTRMKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSKNPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVY-KTGIE--NFET----ARRLFLENKGELLPNSPIQYETATEMKSRFLECMSKYRE---HQTVVVVAHRMLMRQFVPN-----------EKIDFCQVIECELEI 4IJ5 Chain:A ((1-185)) --------------------MVKLILVRHAESEWNPVG--RYQGL--LDPDLSERGKKQAKLLAQELSREHLDVIYSSPLKRTYLTALEIAEAKNLEVIKEDRIIEIDHGMWSGMLVEEVMEKYPEDFRRWVE---EPHKVEFQGGESLASVYNRVKGFLEEVRKRHWNQTVVVVSHTVPMRAMYCALLGVDLSKFWSFGCDNASYSVIHME-

General information: TITO was launched using: RESULT: Template: 4IJ5.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 811 -52166 -64.32 -318.09 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -64.32 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.422

(partial model without unconserved sides chains): PDB file : Tito_4IJ5.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4IJ5-query.scw PDB file : Tito_Scwrl_4IJ5.pdb: