Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEEFTAKFEAVIEGL---DDFLVFADLLGGTPCNVVSRLIME-----GRDIDLYAGMNLPMVIEFINASLT--G-ADA--DYKSRAAESIVKVNDLLAGFDDDEDE 3IPR Chain:D ((1-140)) -MLGIVIATHGALSDGAKDAATVIMGATENIETVNLNSGDDVQALGGQIKTAIENVQQGDGVLVMVDLLSASPYNQAVLVINELEPALQKKIFVVSGTNLPMVLEAINHQLLGTPIAEAAQAIVAQGKESVQAWDISMTSF------

General information: TITO was launched using: RESULT: Template: 3IPR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain D - contact count / total energy / energy per contact / energy per residue : 624 -59021 -94.58 -464.73 target 2D structure prediction score : 0.71 Monomeric hydrophicity matching model chain D : 0.78 3D Compatibility (PKB) : -94.58 2D Compatibility (Sec. Struct. Predict.) : 0.71 1D Compatibility (Hydrophobicity) : 0.78 QMean score : 0.608

(partial model without unconserved sides chains): PDB file : Tito_3IPR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3IPR-query.scw PDB file : Tito_Scwrl_3IPR.pdb: