Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWITVLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKKLGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWKKMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTGDYAHRL-RQLGIEAHKFNKVIPRLTV--AYNNRDHRKILIVDGQIAYTGGVNL-ADEYINHVERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLEN----------------------------------HSIPSDGLTIPYGSGP-------------------KPIFRAQVGKKVYQSLINQATESVYITTPYLII--------DYDLTETIKNAAMRGVDVRIITPYIPD----------------KKFIQLVT--RGAYPDLLSAGVRIYEYSPGF-----------IHSKQMLVDEDFAVVGTINLDYRSLVHHYENAVLLYKTPSIREIARD-FRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAPIL 1F0I Chain:A ((1-504)) --------AATPHLDAVEQTLRQV-------------SPGLEGDVWERTSGNKL------DGSAADPSDWLLQTP----GC-----WGDDKCADR---------------VGTKRLLAKMTENIGNA-------------TRTVDISTLAPFPNG-AFQDAIVAGLKESAA-------------------------KGNSLKVRILVGAAPHMNGIPSKYRDKLTAKLGKAAENITLNVASMTTSKTAFSWNHSKILVVDGQSALTGGINSWKDDYLDTTHPV---SDVDLALTGPAAGSAGRYLDTLWTWTCKNKSNIASVWFAASGNAGCMPTMHKDTNPKASPATGNVPVIAVGGLGVGIKDVDPKSTFRPDLPTASDTKCVVGLHDNTNADRDYDTVNPEESALRALVASAKGHIEISQQDLNATCPPLPRYDIRLYDALAAKMAAGVKVRIVVSDPANRGYSQIKSLSEISDTLRNRLANITGGQQAAKTAMCSNLQLATFRSSPNGKWADGHPYAQHHKLVSVDSSTFYIGSKNLYPS---WLQDFGYIVESPEAAKQLDAKLLDPQWKYSQETATVDYARGICGA-------------

General information: TITO was launched using: RESULT: Template: 1F0I.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2166 -4665 -2.15 -11.63 target 2D structure prediction score : 0.57 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : -2.15 2D Compatibility (Sec. Struct. Predict.) : 0.57 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.398

(partial model without unconserved sides chains): PDB file : Tito_1F0I.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1F0I-query.scw PDB file : Tito_Scwrl_1F0I.pdb: