Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRNFIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLKKKLREDFPQYQWELKNQVYMHQHSPHTASYTSSRDAMSKYPERCTAVGLRLNEESDFELYVPYGLEDILNFQVRPTPHFLENEDRMELYQTRLSKKNWQEKWKNLIFKNT 2LA3 Chain:A ((2-191)) MNTVKNKQEILEAFRESPDMMAILTIIRDLGLKDSWLAAGSVRNFIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQHSPHTASYTSSRDAMSKYPERCTAVGLRLNEELDFELYVPYGLEDILNFQVRPTPHFLENEDRMELYQTRLSKKNWQEKWKNLIFKNT

General information: TITO was launched using: RESULT: Template: 2LA3.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 832 -85619 -102.91 -450.63 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.99 3D Compatibility (PKB) : -102.91 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.99 QMean score : 0.708

(partial model without unconserved sides chains): PDB file : Tito_2LA3.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2LA3-query.scw PDB file : Tito_Scwrl_2LA3.pdb: