Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIDIQGIKEALPHRYPMLLVDRVLEVSED-TIVAIKNVTINEPFFNGHFPQYPVMPGVLIMEALAQTAGVLEL-SKPENKGKLVFYAGMDKVKFKKQVVPGDQLVMTATFVKRRGT--IAVVEAKAEVDGKLAAS-GILTFAIGN 3AZ9 Chain:B ((11-152)) -IDIEDIKKILPHRYPFLLVDKVIYMQPNKTIIGLKQVSTNEPFFNGHFPQKQIMPGVLQIEALAQLAGILCLKSDDSQKNNLFLFAGVDGVRWKKPVLPGDTLTMQANLISFKSSLGIAKLSGVGYVNGKVVINISEMTFAL--

General information: TITO was launched using: RESULT: Template: 3AZ9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 607 -64242 -105.83 -468.92 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain B : 0.84 3D Compatibility (PKB) : -105.83 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.84 QMean score : 0.551

(partial model without unconserved sides chains): PDB file : Tito_3AZ9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3AZ9-query.scw PDB file : Tito_Scwrl_3AZ9.pdb: