Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSRVRVQIMNQFHRKSHEYKAIKRYWKLIQQDSRKLSDKR----FYRPTFRMHLTNKEILDKILSYSEDLKHHYQIYQLLLFHFQNKDPEKFFGLIEDNLKQVHPIF------QTVFKTFLKNKEKIVNALQLPYSNAKIGSDQ 2MN2 Chain:A ((1-122)) --------MDEYSPKRHDVAQLKFLCESLYDEGIATLGDSHHGWVNDPTSAVNLQLNDLIEHIASFVMSFKIKY------------PDDGDLSELVEEYLDDTYTLFSSYGINDPELQRWQKTKERLFRLFSGEYISTLMKT--

General information: TITO was launched using: RESULT: Template: 2MN2.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 417 -17521 -42.02 -156.44 target 2D structure prediction score : 0.74 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -42.02 2D Compatibility (Sec. Struct. Predict.) : 0.74 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.477

(partial model without unconserved sides chains): PDB file : Tito_2MN2.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2MN2-query.scw PDB file : Tito_Scwrl_2MN2.pdb: