Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQGFLPIENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATCLVRGLRNASDLQYEASFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEKKD 4F3R Chain:B ((4-158)) -MKPIAIYPGTFDPLTNGHVDIIERALPLFNKIIVACAPT------LKLEERVNLIADVLTD-ERVEVLPL-TGLLVDFAKTHQANFILRGLRAVSDFDYEFQLAHMNYQLSPEIETIFLPAREGYSYVSGTMVREIVTLGGDVSPFVPPLVARHLQK----

General information: TITO was launched using: RESULT: Template: 4F3R.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 681 -112999 -165.93 -758.38 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain B : 0.84 3D Compatibility (PKB) : -165.93 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.84 QMean score : 0.620

(partial model without unconserved sides chains): PDB file : Tito_4F3R.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4F3R-query.scw PDB file : Tito_Scwrl_4F3R.pdb: