Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEIDDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDILKVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRISAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVEDENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLAEFAGLADALKGQGL 3FUX Chain:C ((4-268)) --LASPQSVRALLERHGLFADKRFGQNFLVSEAHLRRIVEAARP-FTGPVFEVGPGLGALTRALLEAGAEVTAIEKDLRLRPVLEETLS-GLPVRLVFQDALLYPWEE-------VPQGSLLVANLPYHIATPLVTRLLKT-GRFARLVFLVQKEVAERMTARPKTPAYGVLTLRVAHHAVAERLFDLPPGAFFPPPKVWSSLVRLTPTGAL-----DDPGLFRLVEAAFGKRRKTLLNALAAAGY---P-KARVEEALRALGLPPRVRAEELDLEAFRRLREGLE----

General information: TITO was launched using: RESULT: Template: 3FUX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 1373 -196210 -142.91 -740.42 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain C : 0.79 3D Compatibility (PKB) : -142.91 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.523

(partial model without unconserved sides chains): PDB file : Tito_3FUX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3FUX-query.scw PDB file : Tito_Scwrl_3FUX.pdb: