Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKIRQSILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLNVGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL 5T5D Chain:A ((7-161)) -SIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQSILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLNVGQMS-----EKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL

General information: TITO was launched using: RESULT: Template: 5T5D.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 739 -116202 -157.24 -774.68 target 2D structure prediction score : 0.75 Monomeric hydrophicity matching model chain A : 0.99 3D Compatibility (PKB) : -157.24 2D Compatibility (Sec. Struct. Predict.) : 0.75 1D Compatibility (Hydrophobicity) : 0.99 QMean score : 0.629

(partial model without unconserved sides chains): PDB file : Tito_5T5D.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5T5D-query.scw PDB file : Tito_Scwrl_5T5D.pdb: