Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRIIKEPVMSEFEGKSGKWAWEIQKEQQANLDELRSSIEYLVQKYKHDAHASSIFG-----DQDKTRIYNRFVNQLEHLLKGDA 4Z8T Chain:A ((20-98)) ------PGRWEYLANPGNWHPERRKLHEKLLDQARSSALTLAESLESDGCQPTLFALRGNTATGKTRIATKKIPVLAAALKKTA

General information: TITO was launched using: RESULT: Template: 4Z8T.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 97 1627 16.77 22.28 target 2D structure prediction score : 0.74 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : 16.77 2D Compatibility (Sec. Struct. Predict.) : 0.74 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.466

(partial model without unconserved sides chains): PDB file : Tito_4Z8T.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4Z8T-query.scw PDB file : Tito_Scwrl_4Z8T.pdb: